| These substances stimulate the nociceptors at the related area and lead to local sensitivity. |
| The skin also has pain receptors called nociceptors Pain is a subjective perception of an unpleasant sensation which originates in a specific region of the body. |
| Abstract Capsaicin, the pungent ingredient of hot peppers, has long been used to identify nociceptors. |
| This causes the nociceptors to generate nervous impulses, which are transmitted along the fibre into the spinal cord. |
| Thus, the mechanical compression of bone tissues and the algogenic substances released by the bone environment and tumor at day 8 are not sufficient to exacerbate nociceptors and stimulate abnormal neuronal firing. |
| The transduction of noxious stimuli begins with peripheral nociceptors. |
