| The alpha-synuclein protein, which is found broadly in the brain, has been implicated in several neurodegenerative disorders. |
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| One explanation is that altered mental state is indicative of some underlying neurodegenerative process not recognized at the time of admission. |
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| The neurodegenerative changes leading to clinical Alzheimer's disease may begin in middle age. |
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| Memory loss that impairs function suggests neurodegenerative dementia, which is defined as a decline in two or more cognitive domains. |
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| The challenge will be in identifying the biochemical changes associated with mutations for each neurodegenerative disease. |
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| Furthermore, many of the proteins encoded by genes implicated in neurodegenerative diseases interact with cytoskeletal proteins. |
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| These shape changes seem to be tied to onset of symptoms and may be neurodegenerative in nature. |
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| Drugs inhibiting the enzyme would prevent cell death, the goal in treating stroke and neurodegenerative diseases. |
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| Other timely subjects included in this section are amino acid transmitters and neurodegenerative disorders. |
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| It can be used to stimulate areas of the brain that were previously inactive due to injury or neurodegenerative processes. |
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| Using this strategy, we have identified 15 mutations affecting at least nine loci that cause gross neurodegenerative pathology. |
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| Studies in Drosophila have been used to improve our understanding of human neurodegenerative diseases. |
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| Some New Mexicans have been diagnosed with neurodegenerative afflictions which disappeared when they stopped consuming aspartame. |
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| Alzheimer's disease is a neurodegenerative disorder characterized by progressive loss of memory and cognitive function. |
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| The researchers hypothesize that the pronounced loss of these neurons could be caused either by a neurodegenerative process or an autoimmune response. |
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| An estimated 8.6 million people in Europe suffer from neurodegenerative diseases, with Alzheimer's disease in the lead. |
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| Under certain circumstances it can be an excitotoxin and appears to cause nerve cell death in a variety of neurodegenerative disorders. |
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| Upon completing her internship, she plans to continue to study the cognitive and neuropsychological changes associated with neurodegenerative disorders. |
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| Alzheimer's, a neurodegenerative disease, is a common one among older adults. |
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| Parkinson's disease is a common neurodegenerative disorder, predominantly of the elderly, manifested by rigidity, tremors and movement difficulty. |
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| Despite the advances of modern therapies that treat the symptoms, most of the neurodegenerative diseases still remain uncured. |
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| Baker knows firsthand the devastating effects of MSA, a neurodegenerative terminal illness that causes slurred speech and loss of muscle coordination. |
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| It will involve Member States engaging voluntarily in the development of a Strategic Research Agenda establishing medium to long term research needs and objectives in the area of neurodegenerative diseases. |
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| At present neurodegenerative diseases represent one of the main causes of incapacity among the elderly, and the number of people affected is expected to rise significantly. |
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| In 2001, researcher Anders Ahlbom carried out several meta-analyses to determine if there was any link between exposure to EMFs and neurodegenerative diseases or psychological disorders. |
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| Our research program focuses primarily on neurodegenerative diseases such as stroke, Alzheimer's and Parkinson's, and vaccines and immunotherapies against infectious diseases. |
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| Genzyme's commitment to innovation continues today with a substantial development program focused on these fields, as well as cardiovascular disease, neurodegenerative diseases, and other areas of unmet medical need. |
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| The outcome of the proposed research may also provide important insights into other neurodegenerative diseases, because mitochondrial dysfunction is a common feature of all neurodegenerative disorders. |
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| The use of embryonic stem cells may significantly change our ability to combat diseases such as Parkinson's, Alzheimer's, Multiple Sclerosis and other neurodegenerative diseases. |
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| With this aim, sanofi-aventis is multiplying and diversifying its pharmacological and scientific approaches in two major areas: psychiatric disorders and neurodegenerative disorders. |
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| Many neurodegenerative diseases, including Alzheimer's disease, involve pathological protein deposits. |
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| In this respect, therapy using bee and wasp venoms is considered a psychoneurological approach for autoimmune and neurodegenerative diseases. |
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| Several have suggested that this phenomenon may be due to HIV-induced neurodegenerative processes of thermoregulatory centers of the brain. |
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| Transmissible spongiform encephalopathies, also known as prion diseases, are fatal neurodegenerative disorders that affect humans and animals. |
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| We now propose that, following brain damage or neurodegenerative diseases, proNGF alters the glial cell network to change its function. |
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| It is a fatal neurodegenerative disease of the CNS in sheep, goats and mouflons. |
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| Alzheimer's disease is a progressive, neurodegenerative disease. |
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| The new research teams will work on major health issues such as neurodegenerative diseases, pain, depression, cerebrovascular accidents, and the mechanisms of drug dependency. |
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| The Centre for Neuronal Survival that investigates mechanisms of nerve cell death occurring as a result of stroke, epilepsy, cancer and neurodegenerative diseases. |
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| Alzheimer's disease is a chronic neurodegenerative disorder characterized by progressive memory loss associated with the deposition of neuritic plaques in the brains of patients. |
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| What accounted for the neurodegenerative disorder that the people of Guam, the Chamorros, call lytico-bodig? |
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| The abnormal activation and division of astroglial cells in neurodegenerative states like Alzheimer's disease may trigger their abnormal production of neuroactive substance that ultimately result in cholinergic cell atrophy. |
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| Interestingly, inhibition of autophagy partially rescues the neurodegenerative phenotype and activation of autophagy exuberates symptoms in A β42 Drosophila models. |
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| Its neurotrophic and neuroprotective efficacies have been shown following in vitro and in vivo studies in numerous central or peripheral neurodegenerative models, as either curative or preventive treatment. |
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| The goal is to combine EnVivo's neuropharmacology expertise with MethylGene's HDAC chemistry expertise in order to design, discover and develop HDAC inhibitors for neurodegenerative diseases. |
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| One research focus is the characterization of the role of glycosyltransferases in the generation of glycoconjugates involved in neurogenesis, differentiation, synaptic function and neurodegenerative disease. |
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| Special areas of interest include epilepsy, neuroimmunology, molecular neurobiology and genetics, neurodegenerative disease, neuromuscular disorders, movement disorders and brain tumors. |
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| This neurodegenerative pathology is also characterized by an inflammatory state that can be linked to the presence of Ab and to the activation of glial cells. |
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| It is a neurodegenerative movement disorder, but there are several non-motor symptoms that may cause a considerable burden to the patient, such as depression, anxiety, cognitive impairment and psychosis. |
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| Huntington's Disease is an aggressive, neurodegenerative disorder which causes loss of co-ordination, psychiatric problems, dementia and death. |
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| Prion diseases are rare fatal neurodegenerative conditions that affect humans and animals. |
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| Researchers also fed vervet monkeys fruit laced with BMAA, and found that the animals had developed neurofibrillary tangles and plaque which are linked to neurodegenerative diseases. |
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| Lexicon, for example, is analysing 5,000 mouse genes and studying the physiology and behaviour of mice to discover novel drug targets in a number of areas, including cognitive and neurodegenerative disorders. |
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| According to experts this discovery could be important for future research on the recovery of patients with brain injuries or with neurodegenerative diseases such as Alzheimer. |
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| Mitochondrial dysfunctions are associated with a range of pathologies such as cancer, diabetes, neurodegenerative diseases, migraine and infertility. |
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| Chronic conditions, such as obesity, cardiovascular disease, diabetes, arthritis and neurodegenerative disorders, also take a significant toll on Canadians' productivity and well-being. |
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| A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain, leading to loss of mental functions such as memory and learning. |
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| It is a progressive neurodegenerative disease characterized by muscle atrophy, weakness, fasciculations, and hyperactive reflexes. |
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| Warwick researchers will use the fruit fly as a model in their research into Alzheimer's, a progressive neurodegenerative disorder. |
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| Prana Biotechnology was established to commercialise research into Alzheimer's disease and other major age-related neurodegenerative disorders. |
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| The study is the first to show that tolerance induced by preconditioning can protect against a neurodegenerative disease. |
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| MitoKor is the first company to advance cybrid models for neurodegenerative diseases, such as Alzheimer's and Parkinson's, and metabolic disorders such as type II diabetes. |
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| Neurodegenerative diseases causing transmissible spongiform encephalopathies are the subject of intense research. |
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