“The more common episomal pattern appears as a dense, opaque, blue oval that overlies the majority of the central portion of the target cell.”

“We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes.”

“Although it is possible that these extra ND5-like sequences exist as extrachromosomal, episomal DNA, several lines of evidence suggest they are of nuclear origin.”