The gene could be mutated during transcription into the genetic code, and could perhaps make any genetic problem even worse. |
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Using a technique called X-ray crystallography, they worked out the virus's structure and saw that it had mutated. |
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Much of the remaining junk DNA in our genome may also turn out to be former transposable elements that have mutated beyond recognition. |
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But this one combines his growing sense of time with a subtly mutated idiom in an unutterably cute three-word package. |
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As the monster travelled and mutated, it also accreted ever more complex layers of meaning. |
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Low molecular weight oligomers were found in culture media of Chinese hamster ovary cells expressing endogenous or mutated genes. |
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Sure, by loose definition it can be called a game, but it has mutated into something much more grotesque than that. |
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This friendship also mutated into something more, as we already had the hugging scenes, and then this. |
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America, once known as the land of the free and the home of the brave, has mutated into the land of the medicated and the home of the lawsuit. |
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Only 15 of these genes were previously known to cause a toxin phenotype when mutated. |
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Valen's counterfeit mutated into a destructive alter ego that was usually kept safely secluded in the subconscious. |
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He said the bug, mutated bacteria found in the gut, was identified by microbiologists several years ago and was widespread throughout the world. |
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This gene, when mutated, severely disrupts both germ cell migration and developmental cell death. |
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The festival seems to have mutated from a charming harvest festival to an annual beer and sausage pig-out. |
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To identify factors important for repeat-mediated deletion, we disrupted or mutated putative yeast mitochondrial recombination genes. |
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Come next year these unexceptional throwbacks might have mutated into cunning reinventors. |
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The pigeon let out one long coo, and then, as its body began to swell and transform, the sound mutated into a low chuckle. |
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Somehow, they've mutated into characters who are colder, harder, and much less moral. |
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We had our reunion yesterday, attended by 11 of us which is a good turn out, and the day trip to France has now mutated into a weekend in Paris! |
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But by 2005, the European agenda has mutated into making a new class of politicians more powerful. |
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Additional genes important for eye development may remain unidentified because they cause early lethality when mutated. |
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He had mutated into one of the earth's most evil and cruel creatures imaginable. |
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Fruit growing in gardens and fish from the local rivers are mutated and inedible. |
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What was once the realm of science fiction has mutated into serious debate. |
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Then my pleasant thoughts mutated into dark gory battlefields across the red sand. |
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In some awful way, his regard for the underdog has mutated into support for mad dogs. |
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A mutated sequence is considered thermodynamically stable if both computational parameters are above predetermined thresholds. |
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Dr. Ingrid Skinner disappeared with a number of theroid specimens that have mutated into monsters. |
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Why has our understanding of democracy mutated into nothing but an allergy to order and responsibility? |
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I mean, I have no problems with research that disprove age-old theories that already mutated into dogma. |
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Nowadays the car has cleverly mutated into a hatchback but even so, a bag of golfclubs is out of the question. |
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The Glasgow-based band's debut delivers on its promises of glam-rock mutated into disco rhythms with interest. |
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It developed on the east coast, mutated into different forms, spread to Europe and on. |
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Both transcripts from the mutated allele are thus likely to encode completely nonfunctional GLB1 proteins. |
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But now the perennial moaning about diving has mutated into a full-blown campaign to stamp out this malevolent practice. |
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Famine had mutated into an invincible monstrosity that was ravaging more than half of Africa's children. |
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But perhaps the dreadful birth defects and mutated plants are not evidence at all, but signs and wonders portending some great event. |
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Floating in glass-topped court-tank of aquamarine. Underwater wave lengths of muffled sibilance, mutated boom. |
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The artist depicts himself sketching a fantastically mutated tree, seated beneath its dense canopy of leaves and vines. |
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The scene climaxes with the space travelers' violent encounter with the planet's horribly mutated inhabitants. |
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When the mutated genes were inherited, the disinclination towards wealth exposure passed on. |
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The vaccine would not be effective against a mutated virus as virologists can only start work once the strain has been isolated. |
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New mutated forms of GFP that are more intensely fluorescent provide more avenues for its use in vertebrate systems. |
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A mutated version of the gene is related to a lowered ability to stop eating, as well as a susceptibility to hunger. |
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Alternatively, it may have derived from one or more unidentified animal coronaviruses that only recently mutated or recombined to create a human pathogen, he says. |
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However, scientists are trying to dampen down any fears about the spread of the disease which so far has not mutated into a form that can spread among humans. |
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Slowly, his astonishment mutated into a face of contorted devilry. |
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By using existing modernist architecture for locations, and having their characters speak a mutated form of English, they persuasively create a high-tech dystopia. |
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Three decades later and Constance, by now a barrister, repaid the favour by successfully acting for the school when it mutated into a hotel and sought a liquor licence. |
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A protooncogene only becomes oncogenic when it is overexpressed or when its sequence is mutated. |
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Those it takes longest to find are then mutated slightly and crossbred to create a new generation. |
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It's like you've mutated and suddenly you have a totally different skill set. |
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By randomly mutating these genes and then breeding them with other, similarly mutated genomes, new offspring designs are created. |
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But three weeks later the mutated mice suddenly began to drink much more alcohol. |
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Thankfully it has not mutated into a human strain yet, but it behaves in a different way in different birds in different regions. |
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Presumably, vaccinia virus with the mutated gene would be much more pathogenic. |
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During the research normal and mutated mice were first offered a choice between water and ethanol solutions at different concentrations. |
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There is no evidence whatever to suggest that bird flu has mutated and can be passed between human beings. |
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In the opposite case, where gene changes are harmful, the mutated gene will be rapidly erased from the population by natural selection. |
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Plant cells and tissues can be intentionally mutated through large-scale mutagenesis or mutation breeding to select model types. |
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Although the researchers did not actually outfit vaccinia virus with this mutated gene, the work was only one step away from this manipulation. |
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Amphibians are disappearing at an alarming rate and many, while still around, are strangely mutated. |
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To some extent, the political violence of the 1980s has mutated into the criminal variety. |
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He emerged as a hideously mutated fly-human-fusion-creature. |
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The complete molecular analysis of the mutant, including the complementation of the mutated gene, is currently being completed and will be reported separately. |
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The marauding, man-eating Titans are mutated, androgynous beasts that have no need to feed but love to kill. |
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In the hands of the Protestant exiles in the 1550s, conciliarism mutated into forms of resistance theory which justified regicide or the deposition of kings. |
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Police now acknowledge that the red-light district has mutated into a global hub for human trafficking and money laundering. |
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Nothing would be nicer than to hear a filmmaker backtrack and recall how studio tinkering hampered his vision, or how test audience ambivalence mutated his masterwork. |
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Once masters of the situation, it is said, the zeal of those who promised reform mutated into a zeal to preserve their private wealth and that of their friends. |
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Instead, at this pace Smith brings the reader right around to the conflicts of Soviet old, but mutated thanks to added plutocracy. |
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These are single genes that, when mutated, greatly increase your risk for developing a specific disease. |
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The Internet basically exploded and then caved in on itself and then mutated into an alien cyborg in response. |
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Autograph hunters have gradually mutated into poison-pen letter-senders. |
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The sequence of the two nonconserved regions, NC1 and NC2, is shown, with the nucleotide substitutions in mutated oligos shown above the wild-type sequence. |
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The C. difficile bacteria causes severe diarrhea and may have mutated into a virulent superbug over the past couple of years, according to reports. |
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Her current work is focusing on the SUMO protein, discovered in the 1990s, which can also alter the structure of the mutated retinoic acid receptor. |
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Oncolytics Biotech has been developing a method of utilizing a reovirus to target and kill cancers that exhibit mutated RAS pathway activity. |
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The SNP5-Scall locus was located at intron 3 and mutated from A to G, which could be genotyped by the Scall PCR-ACRS-RFP method. |
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But the separateness of mitochondrial genes means that by moving the nucleus from an afflicted egg into a healthy one, the mutated, disease-causing genes can be left behind. |
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It occurs in a child only if both parents pass on the mutated gene. |
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This gene is mutated in over 20 per cent of children and allows researchers to establish the genetic basis for hereditary blindness in up to 75 per cent of patients. |
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Consequently, in order to learn of a cytoplasmic determinant serving a specific hereditary function, one must detect it in a mutated form. |
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An effective vaccine will induce responses against a portion of the virus that does not change very often, allowing protection even when the virus has mutated. |
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A pandemic influenza will be caused by a newly formed or mutated virus for which the population at large will have limited immunity, increasing its contagiousness. |
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Hansford Worth who pointed out that the correct Celtic form would have been maen fawr, so it could not have mutated into Bowerman. |
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Be on your guard as these mutated creatures are exceptionally strong. |
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Whippet breeders have, unintentionally, selected for their dogs to carry the mutated myostatin gene. |
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Regular aspirin use has been linked to a lower risk of BRAF wild-type, but not BRAF mutated, colorectal cancer, according to a report. |
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He highlighted the risk of a global pandemic of avian influenza the event that the virus mutated into a form capable of human-to-human transmission, and pointed out that the Asian and Pacific region could be the hardest hit. |
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The Daleks are Kaleds from the planet Skaro, mutated by the scientist Davros and housed in mechanical armour shells for mobility. |
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More recently, the researcher proved that arsenic, a substance used in the treatment of certain leukemia, also has the ability to alter a mutated retinoic acid receptor. |
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One of the mutated genes is RBFOX2, which encodes a molecule that regulates RNA splicing. |
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From 1660 onwards, new dramatic genres arose, mutated, and intermixed very rapidly. |
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The transposons instructed zebrafish cells to mark mutated proteins with a fluorescent protein 'tag. |
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The overall goal of this key action is to combat established, emerging or re-emerging infectious diseases including zoonoses, linked to old, new or mutated agents in humans or animals. |
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Stellar box office figures, sobbing acclaim and – astonishingly – near-blockbuster status in the US, means that Paddington has mutated into a bona fide cinematic hit. |
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Comparison of the sets of mutated genes from different examples of the same tumour will show which mutations are coincidences, and which are causes. |
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It was observed that the nerve cells of mutated mice responded more strongly to artificial stimuli than was the case for mice in the control group. |
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If that is the case then why hasn't the ordinary influenza mutated into some horrible disease? |
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In Huntington's disease, a mutated protein in the body becomes toxic to brain cells. |
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An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson's disease. |
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There, a team began the search for the mutated gene that was causing the twins' problems. |
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Mendelian diseases are those caused by a single mutated gene and are also known as monogenic disorders. |
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It is possible that some of the stories about Hereward mutated into tales about Robin Hood or influenced them. |
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Those who have two copies of a mutated gene called Neuromedin beta may be twice as likely as others to experience feelings of hunger, making them more likely to overeat and to become obese. |
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It seems that the mutated ABCA 12 gene in harlequin ichthyosis has something to do with the production of the lamellar granules in the upper layers of the skin. |
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The sequenceverified wild-type Bcl-2, mutated Bcl-2, and pLNCX2 empty vector plasmid were transfected separately into the BD RetroPACK PT-67 cell line. |
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The gene that encodes filaggrin, an epidermal barrier protein produced by differentiating keratinocytes, is often mutated and can be a causative factor for eczema. |
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This hybrid, the team found, produced greater yields because there was one normal copy and one mutated copy of a single gene that produces a protein called florigen. |
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Unlike organisms, a gene is passed down from a generation of organisms to the next generation either as perfect replicas of itself or as slightly mutated descendant genes. |
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The drugs, by halting or slowing growth of some cancer cells, may have left room for small groups of already mutated or newly mutated cells to take over the tumor. |
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I am not sure whether it is with resignation or reflection that we should face the fact that our politics have mostly mutated into hollow fights and Pyrrhic victories. |
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Mammals need two genes to make the taste receptor for sugar. Studies in various cats showed that one of these genes has mutated and no longer works. |
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Two genes that are known to influence melanin production, LYST and AIM1, are both mutated in polar bears, possibly leading to the absence on this pigment in their fur. |
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Until now, even though ARF was known to be expressed in some tumors with mutated p53, ARF largely was thought to be nonfunctional in this scenario. |
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The shotgun entered the century as a flintlock, mutated into a percussion lock and finally evolved into the side-by-side breechloader we know today. |
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The SNP1-Taql locus was located at exon 2 and mutated from G to A, resulting in a missense mutation, CGA to CAA, which could be genotyped by the Taql PCR-RFP method. |
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