“In endemic areas such as Africa, Asia, and South America there is a relatively high seroprevalence of antibodies to the organism.”
“Andaman Islands is a highly endemic area for leptospirosis 4,5-8 with more than 50 per cent seroprevalence.”
“In addition, because HIV infection was a risk factor for serious adverse reactions, incidence may be higher in populations with higher HIV seroprevalence.”