“If the plugged follicle, or comedo, stays beneath the skin, it is called a closed comedo and produces a white bump called a whitehead.”

“In our case, the senile degeneration of connective tissue is suspected to be the occasion of comedo formation.”

“If the plug enlarges and is on the surface of the skin, exposed to the air, it is called an open comedo, or blackhead.”

“It most often manifests in adolescents as comedones, papulopustules, and nodulocysts.”

“This results in enlargement of the sebaceous glands, which can eventually lead to the development of comedones.”

“If the lipid material accumulates in the hair follicle, we have the formation of comedones, or blackheads.”