| We have furthermore determined that urate microcrystals altered the phenotype of human neutrophils into a highly pro-inflammatory program. |
| Diagnosis is by removing fluid from an affected joint or tophus and identifying urate crystals under a polarized-light microscope. |
| Their urinary urate concentrations rose after they ate cherries, with peak excretion taking place three hours later. |
| These urate results strongly suggest that cherries can play an important role in fighting gout. |
| In most cases of gout decreased urinary excretion of urate is the most common metabolic abnormality. |
| Additional rapid destruction of granulocytes may accompany the initiation of chemotherapy and increase the urate pool. |
