For totipotent stem cells which are the blastomeres of the embryo in vitro, as it is presently formulated, the law forbids cell sampling. |
Now these cells are considered to be totipotent, or near totipotent, so there's a discussion as to whether they can make any cell type of the body or some of them. |
Thus, unlike totipotent single-cell embryos, pluripotent embryonic stem cells are specialized cells that have limited developmental capabilities. |
In this case it is only the product of cell nucleus transfer that is to be defined as totipotent and not the original cell. |
Here, human or mouse embryonic stem cells, in vitro representatives of the totipotent inner cell mass blastomeres, are placed into culture. |
In general a distinction is made between totipotent and pluripotent embryonic cells. |