From a screen of 24,000 mutagenized flies, 17 mutants with presynaptic defects in synaptic transmission were recovered. |
Depolarization of the presynaptic membrane causes release of acetylcholine into the synaptic cleft. |
A variety of experiments indicate that single synaptic connections exhibit a broad distribution of presynaptic release probabilities. |
Such tendon jerks are tested as part of a routine neurological examination, to assess the state of synaptic connections. |
But this is not to suggest that Hebb's influence was just his postulates related to synaptic change. |
When postsynaptic receptors are saturated, a quantum of synaptic current corresponds to the response evoked in a single synaptic bouton. |