| The normal degradation of the sulphoxide to the sulphone is not affected. |
| The two major metabolites of aldicarb, the sulphoxide and the sulphone, are also acetyl-cholinesterase inhibitors, with the sulphoxide approximately equipotent with the parent compound and the sulphone somewhat less potent. |
| Both the sulphoxide and the sulphone are then degraded into unidentified products. |
| Dominant lethal mutations were not induced by aldicarb or aldicarb sulphone in studies in which treated male rats were mated with unexposed females. |
| This guideline is considered to be applicable to the total of aldicarb and its toxic metabolites, aldicarb sulphoxide and aldicarb sulphone. |
| Ingested aldicarb sulphoxide and aldicarb sulphone are metabolized in the same manner as the parent compound. |
