| Both the sulphoxide and the sulphone are then degraded into unidentified products. |
| The two major metabolites of aldicarb, the sulphoxide and the sulphone, are also acetyl-cholinesterase inhibitors, with the sulphoxide approximately equipotent with the parent compound and the sulphone somewhat less potent. |
| Aldicarb is rapidly oxidized to aldicarb sulphoxide, which is further metabolized more slowly by oxidation and hydrolysis to aldicarb sulphone. |
| The chloroform layer was evaporated and the product of this reaction was identified as diphenyl sulphone. |
| Success by others in identifying two sulphone compounds with potential therapeutic effect in experimentally infected animals heralded the need for clinical trials in humans. |
| Aldicarb and its by-products, aldicarb sulphoxide and aldicarb sulphone, inhibit acetyl-cholinesterase in the nervous system. |
