| The sulphone, desmethylthioether and mercapturic acid conjugate minor metabolites were observed at lower levels. |
| This guideline is considered to be applicable to the total of aldicarb and its toxic metabolites, aldicarb sulphoxide and aldicarb sulphone. |
| Success by others in identifying two sulphone compounds with potential therapeutic effect in experimentally infected animals heralded the need for clinical trials in humans. |
| Ingested aldicarb sulphoxide and aldicarb sulphone are metabolized in the same manner as the parent compound. |
| Aldicarb is rapidly oxidized to aldicarb sulphoxide, which is further metabolized more slowly by oxidation and hydrolysis to aldicarb sulphone. |
| Aldicarb and its by-products, aldicarb sulphoxide and aldicarb sulphone, inhibit acetyl-cholinesterase in the nervous system. |
