Purification of Cryptosporidium oocysts and sporozoites by cesium chloride and percoll gradients. |
Oocytes ingested from contaminated soil or other sources excyst in the duodenum, and released sporozoites invade the intestine. |
The sporozoites migrate to the salivary glands and are inoculated into a new vertebrate host when the mosquito feeds. |
Infection by sporozoites reduces the fecundity of mosquitoes. |
Inside the liver, the sporozoites change form and then grow and divide into thousands of merozoites. |
They then watched as sporozoites traversed Kupffer cells using a special process distinct from ordinary parasite locomotion. |