| Hammerhead ribozymes are small, catalytic RNAs that can be designed to target and cleave substrate RNAs at sequence specific sites. |
| This view has been strengthened by the discovery that some forms of RNA, called ribozymes, can act like non-protein enzymes to catalyze biological reactions. |
| Naturally occurring ribozymes may be used in chemotherapy, but they are large, expensive, and fragile RNA molecules. |
| They placed the DNA copy between two ribozymes, RNA molecules that have enzymatic function and can cleave RNA sequence at specific locations. |
| They can act as real enzymes and, by analogy to protein enzymes, are called ribozymes. |
| Each of these ribozymes and a corresponding non-catalytic control ribozyme was cloned into the shuttle vector, pPCR-Script. |
