| Naturally occurring ribozymes may be used in chemotherapy, but they are large, expensive, and fragile RNA molecules. |
| This view has been strengthened by the discovery that some forms of RNA, called ribozymes, can act like non-protein enzymes to catalyze biological reactions. |
| Gene therapy is also making use of catalytic RNA through the construction of ribozymes. |
| But to do their work, ribozymes need to first get into the cells, and for that they need help. |
| At that time, everyone thought of proteins as the only kind of enzymes and ribozymes had not yet been found. |
| They placed the DNA copy between two ribozymes, RNA molecules that have enzymatic function and can cleave RNA sequence at specific locations. |
