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What does relapsed mean?

Looking for the meaning or definition of the word relapsed? Here's what it means.

Verb
  1. simple past tense and past participle of relapse
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Thirteen patients relapsed after positive response to therapy and developed tumors at pre-existing or new sites within the body.
Ten out of the eleven patients relapsed after discontinuing MPA against medical advice.
One patient relapsed upon discontinuation of clarithromycin therapy but has since responded to re-initiation of treatment.
If patients relapsed, they were crossed over to the other treatment regimen.
In one study, arsenic trioxide was given to patients who relapsed after achieving remission with ATRA and chemotherapy.
The four kingdoms soon relapsed into paganism, and initially only Kent was reconverted.

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