| If there is a recurrence then operative removal of the cyst and its sac becomes necessary. |
| Following lumpectomy, local recurrence is usually at the surgical site and can be treated with mastectomy. |
| Obesity, insufficient excision, significant skin maceration, and chronic skin infection may increase the incidence of recurrence. |
| If an anticonvulsant drug is used, the typical duration of therapy is one year, which represents the period with the highest risk of recurrence. |
| Many patients have at least one recurrence of disease activity during the course of the taper. |
| Pituitary irradiation can induce remission of disease in more than one half of patients with recurrence after surgery. |
