The drug, Paclitaxel, is meant to prevent restenosis, the narrowing of the arterial walls after a stent is inserted to unblock an artery. |
Paclitaxel is the world's largest selling antineoplastic drug. |
Combinations with carboplatin, gemcitabine, paclitaxel, vinorelbine, topotecan, and irinotecan are also used. |
In preclinical and clinical studies at cytostatic doses, paclitaxel has demonstrated promising results for reducing the processes leading to restenosis. |
Standard dosages of paclitaxel and carboplatin will be delivered with escalating dosages of REOLYSIN intravenously. |
Chemotherapy usually consists of a combination of agents, such as hexamethylmelamine, doxorubicin, cisplatin, carboplatin, and paclitaxel. |