| We depleted NT2 cells of their endogenous mtDNA by prolonged treatment with dideoxycytidine, thus creating the desired line. |
| One example of the biological importance of intergenomic coadaptation is the evidence that mtDNA interaction with the nuclear genome modifies cognition in mice. |
| To generate a partial mtDNA genomic library, mtDNA was isolated according to Barriga Sosa et al., followed by CsCl isopycnic centrifugation. |
| However, these cellular mechanisms cannot explain uniparental mtDNA inheritance in isogamous species with equal-sized and undifferentiated gametes. |
| However, the clonality of human mtDNA has recently been questioned and keenly debated. |
| We assume that every mtDNA molecule has an equal chance of being partitioned to either daughter cell, regardless of where in the cell it is physically located. |
