Overall drug loading was low, which indicated a greater tendency of the monoacid compound 2 to aggregate and settle out of the formulations. |
For these purposes, various hydrophobic groups have been introduced into the DTPA molecule through amidation of monoacid tetraester DTPA derivatives. |
They recently studied the biodistribution of tetra chlorin and benzoporphyrin derivative monoacid ring A in the hamster model. |