The exchanges between top international experts confirm the therapeutic potential of this cytokine in the treatment of immune compromised patients suffering from lymphopenia as well as cancer and chronic viral infections. |
Previously Treated Patients: Severe lymphopenia and a rapid and sustained decrease in lymphocyte subsets occurred in previously treated patients following administration of MabCampath. |
The authors further note that lymphopenia induced by cytotoxic chemotherapy or other insults can significantly diminish immune function. |
Significant and prolonged lymphopenia has been noted. |
Haematological and biochemical parameters were typical of glucocorticoid overdosage and consisted of a moderate to marked leukopenia and lymphopenia and increased erythrocytes, serum enzymes, protein and cholesterol. |
The clinical significance of the prolonged CD4 lymphopenia is unclear. |