Previously we reported that recombinant histidine tagged OspC could be attached onto liposome surfaces by metallochelation. |
Lipid concentrations of liposome suspensions were determined by phosphate analysis. |
When imaging liposome attachment and coalescence to a clean surface, the slides were affixed to a magnetic disk and placed directly into the microscope. |
Briefly, the initially adsorbed liposomes seemed to collapse from the outer periphery toward the center of the liposome. |
The dimensions also suggest that the intact liposome as a sphere should have a diameter of several hundred nanometers. |
The liposome structure can be useful for protecting sensitive molecules that are to be delivered orally. |