On the surface, the process of keratinocyte maturation is disturbed and corneocyte desquamation is delayed. |
The cytological action will be to supply the keratinocyte cells an information destined to calm the abnormal mitosis triggered off by the activation of the genes. |
The first cultured cell type used for therapy was the keratinocyte of the epidermis, for the treatment of burns. |
This genetic illness essentially concerns the keratinocyte cell carriers of the « Psoriasis » genes. |
During this epidermal differentiation, the keratinocyte loses its nucleus, fills with keratin and fabricates the intercorneocytory cement. |
T cell-driven inflammation is responsible for the keratinocyte growth and the angiogenesis seen in the psoriatic plaque, as has become clear in recent years. |