| She began to lose her sight five years ago, causing her to become timid, irritable and even attack animal keepers on occasion. |
| Have you ever noticed that one of your colleagues is particularly irritable, difficult to work with or perhaps even a hyperactive time-waster? |
| That should have ended it, except that certain newspapers have grown irritable and waspish with Tony Blair. |
| Humans with irritable bowel syndrome who have bloating and borborygmus as symptoms have impaired gas transit. |
| Well, I think I'm considerably less grumpy and irritable today than yesterday. |
| Mrs Lewis said she had felt unwell, lethargic, irritable and overweight for many years. |
