| The simultaneous occurrence of random aggregation and amyloid fibril formation has been observed before. |
| Within each fibril are relatively thick filaments of the protein myosin and thin ones of actin and other proteins. |
| Evidently a small quantity of solid fibril network is able to trap a large amount of water. |
| Many such pairs of filaments are bundled together into a structure called a fibril, and groups of fibrils make up a single muscle fiber. |
| Amyloid fibril formation depends on a partial unfolding of the native protein. |
| As the number of fibrils decreases, it becomes increasingly easier to cut the next fibril because the fibrils carry larger and larger loads. |
