Among the ethidium derivatives reported in the literature, the majority are phenanthridine derivatives with modifications of the exocyclic amines. |
The formation of compound 3 proceeds through dehydrogenation and addition of bromine to the exocyclic double bond. |
The sesquiterpene aromadendrene bears a reactive exocyclic methylene group and a cyclopropane ring which can alkylate proteins and thereby disturb the conformation of protein. |