In this study, mice were administered galactosamine and endotoxin, chemical agents that are used to induce endotoxemia resulting in liver failure due to cell death. |
Endotoxemia and sepsis also induce mitochondrial dysfunction, sarcolemmal injury, and weakness and fatigability of the diaphragm. |
Unhealthy food habits increase the production, absorption, and blood levels of lipopolysaccharide, which in turn increase the risk of metabolic endotoxemia. |