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What is a depletion?

What is a depletion? Here are some definitions.

Noun
  1. the act of depleting, or the state of being depleted; exhaustion
  2. the consumption of a resource faster than it can be replenished
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By causing volume and sodium depletion, thiazide diuretics stimulate the production of renin and angiotensin.
Cellular depletion of oxygen results in rapid molecular and physiological acclimation.
Heat exhaustion can be associated with water or sodium depletion, which can compromise the patient's ability to thermoregulate by sweating.
The depletion process is accelerated, however, when cotton is grown in rotation with high K-requiring crops such as alfalfa and corn silage.
The US Delta launch vehicle upper stage now performs such a burn to depletion.
Taken together, these results show that thiram induces GSH depletion, leading to oxidative stress and finally cell death by apoptosis.

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