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What are callouses?

What are callouses? Here are some definitions.

Noun
  1. plural of callous
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Examples
He felt her callouses grind and grate on his, and a great wave of pity welled over him.
His hands were thin, with long fingers unmarked by callouses, and his skin was too white to have been too often outside.
This can lead to blisters, corns, and callouses, and can even contribute to bunion formation.
Or maybe my hands have just grown callouses due to my lack of oven mitt wearing while handling the device.
But there was a sparkle in his eyes, an ease of movement and callouses on his hands.
But the world, which veils the spirit and callouses the instincts, makes curiosity for most people the criterion of interest.

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