| In the Duke experiments, pregnant mice that received dietary supplements with vitamin B12, folic acid, choline and betaine gave birth to babies predominantly with brown coats. |
| This high activity is mainly attributable to the use of 1 M of betaine as a stabilizing cosolute in all preparation and assay media. |
| The supplements also included betaine, which can help bypass any enzyme defect. |
| And while GPC does counteract urea, there is yet no consistent evidence that is a better stabilizer than betaine. |
| Many plant species accumulating betaine inhabit saline and arid areas and accumulate the compound in response to drought and salinity. |
| High levels of betaine are found in shellfish, spinach, wheat germ and mushrooms. |
