| When a malignant tumour no longer resembles the tissue of origin, it is said to be undifferentiated, or anaplastic. |
| We defined advanced stage as nodal or metastatic spread and high grade as poorly differentiated, undifferentiated, or anaplastic disease. |
| Of the 14 anaplastic oligoastrocytomas, 6 were designated astrocytoma predominant and 2 were oligodendroglioma predominant. |
| In their article, 4 of 5 cases were found to have villous or tubulovillous adenomas adjacent to the highly anaplastic carcinomas but with no obvious transition. |
| Finally, a highly anaplastic growth can occur, in which the cancerous cells bear no visible relation to the parent tissue. |
| If you or someone you know has been diagnosed with recurrent or refractory anaplastic astrocytoma and is possibly interested in participating in the SAPPHIRE study, please click here. |
