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What does anaplastic mean?

Looking for the meaning or definition of the word anaplastic? Here's what it means.

Adjective
  1. (oncology) Of, or relating to, a tumor that shows little histogenetic differentiation. It implies that a tumor is high grade and likely to behave in an aggressive fashion.
  2. (surgery) Of or relating to plastic surgery.
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Examples
He was discussing a possible link between the implants and anaplastic large-cell lymphoma or ALCL, a cancer that involves the immune system.
If you or someone you know has been diagnosed with recurrent or refractory anaplastic astrocytoma and is possibly interested in participating in the SAPPHIRE study, please click here.
In their article, 4 of 5 cases were found to have villous or tubulovillous adenomas adjacent to the highly anaplastic carcinomas but with no obvious transition.
There was an increased incidence of mammary tumours with a shift toward more anaplastic forms in female and an increase of thyroid tumours in male rats on the high dose.
Finally, a highly anaplastic growth can occur, in which the cancerous cells bear no visible relation to the parent tissue.
In a series of 285 supratentorial anaplastic gliomas in adults, 10 tumors were classified as anaplastic oligodendrogliomas.

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