| The index case may be treated with the recommended five-day course of zanamivir or oseltamivir, but not amantadine. |
| On the other hand, seasonal H1N1 is sensitive to amantadine while the H1N1 2009 strain is not. |
| To avoid nightmares, amantadine must be taken in the morning and afternoon, never in the evening before going to bed. |
| These effects can also be caused by the administration of anticholinesterases or antihistamines while taking amantadine. |
| The pandemic H1N1 viruses are resistant to adamantanes including amantadine and rimantadine. |
| Administration of amantadine may cause gastrointestinal upset. |
