| Ion channels are transmembrane proteins that regulate ionic permeability in cell membranes. |
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| One of our recent projects was to make use of the rhombohedral crystals to construct the electron density profile of the transmembrane pores. |
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| Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. |
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| The functional role of the transmembrane domain and the cytoplasmic tail domain of fertilin is not known. |
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| By binding intramolecularly to the receptor, the tethered ligand causes transmembrane signaling. |
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| The former is driven by a transmembrane proton motive gradient, whereas the latter is driven by a sodium electromotive gradient. |
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| Pore formation is promoted by an increased likelihood of transmembrane water defects in the presence of an external electric field. |
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| This reaction creates and maintains a transmembrane pH gradient, which provides energy for adenosine triphosphate synthesis. |
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| The transmembrane helix of subunit VIIc changes its angle of inclination midway through the helix. |
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| We conclude from these data that the first transmembrane domain of Css1p is necessary and sufficient for its membrane localization. |
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| The motor is one of the two known molecular rotary engines that derive their energy from a transmembrane ion motive gradient. |
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| Membrane proteins consist of transmembrane proteins and anchored membrane proteins. |
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| Gating currents represent intramolecular motions of ion channels in response to changes in transmembrane potential. |
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| These transmembrane molecules link the cell to laminins and collagen in the basal lamina. |
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| The stator is composed of two transmembrane proteins, MotA and MotB, that surround the MS ring. |
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| It is important for cell surface recognition and transmembrane signaling during T-cell activation. |
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| Cells can be damaged from cell heating, transmembrane loading, and electrochemical effects. |
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| The dye has already proven successful for live cell measurements of transmembrane potential. |
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| Four similar transmembrane domains, of about 300 amino acids each, surround a central aqueous pore through which the ions pass. |
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| The same holds for the application of a transmembrane potential that is limited to the generation of a diffusion potential by the usage of ion-specific ionophores. |
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| The enzymes in F1 then catalyze ATP formation, using both the proton supply and the lamellar transmembrane charge. |
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| They also provide an opportunity to study self-assembly of transmembrane helix bundles, a process believed to be important in the folding of membrane proteins. |
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| For example, dimerization of the transmembrane segment of glycophorin is less tight and equilibrates much faster in sodium dodecyl sulfate than in zwitterionic detergents. |
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| Membrane topology of the FNT family members is consistent with six putative transmembrane helical spanning domains, as established for the FOCA protein of E.coli. |
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| For five years, Gregory Emery has specifically worked on characterizing transmembrane proteins of the p24 Family involved in the Golgi organization. |
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| This transmembrane voltage gradient arises from the presence of ion-specific voltage-sensitive channels that are made up of proteins and are embedded in the lipid layers of the cell membrane. |
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| Some virus types have two outer layers where the outermost envelope consists of a lipid bilayer containing a plethora of transmembrane proteins used for cell recognition. |
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| The specific defective gene that causes CF is the cystic fibrosis transmembrane conductance regulator gene. |
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| Syndecans are cell-surface transmembrane heparan sulfate proteoglycans with a variety of functions in the cell. |
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| The findings from the neutron diffraction work suggest that the poor affinity for PUFA may affect the transmembrane, as well as the lateral, distribution of cholesterol. |
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| Hence, the outer membrane of the chloroplast, which is freely permeable to small molecules, also contains transmembrane channels for the import of larger molecules, including nuclear-encoded proteins. |
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| Connexins are a family of transmembrane proteins that form intercellular gap junction channels to allow ions and small molecules between adjacent cells. |
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| Inflectra is a chimeric humanCaemurine monoclonal antibody that binds with high affinity to both soluble and transmembrane forms of TNF alpha but not to lymphotoxin alpha. |
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| Exon 3 encoded a hydrophilic domain containing multiple stop codons that would result in truncation of MOG prior to translation of its transmembrane domain. |
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| Transmembrane helices in membrane coils predominantly cross at left-handed angles, those in membrane gates predominantly at right-handed angles. |
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| Transmembrane proteins, such as integrins, anchor cells to the substrate. |
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