How to use smooth muscle in a sentence

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Sentence Examples Hair follicles and smooth muscle, sweat and sebaceous glands, and Pacinian corpuscles are located in the reticular layer. The mass also contained cystic spaces lined by columnar epithelium, sebaceous glands, cartilage, smooth muscle, and pancreatic acini. Nitroglycerin causes relaxation of vascular smooth muscle in both arteries and veins, although the effect on veins predominates at low doses. The efflux of potassium ions hyperpolarizes the cell membrane, resulting in vascular smooth muscle relaxation. The areola contains softer and darker skin tissue which surrounds the nipple and which also contains smooth muscle fibers. This drug relaxes arteriolar smooth muscle and has been used in the treatment of severe hypertension. External injury to the alveolar wall may be the counterpart of arteriolar smooth muscle injury. Branched smooth muscle fibers can be found in the nipple of the mammary glands. A microvillous tegument was appreciated overlying a thin layer of smooth muscle and a single row of stromal cells. Oesophagitis may lead to the production and release of inflammatory mediators, which could secondarily alter smooth muscle function. Some veins do not possess smooth muscle fibers and, as a result, do not have a tunica media. This contraction arises from excitation of the circular layer of smooth muscle by autonomic nerves. A portion of the cystic mass showed benign bladder smooth muscle and serosa focally adhered to the outer cyst wall. Neither fascicles of smooth muscle cells nor thick-walled tortuous blood vessels were present. It remains to be shown that W512 is uniquely sensitive to nucleotide binding and hydrolysis in smooth muscle myosin. In addition, muscarinic receptor stimulation augmented the mitogenic responses of human airway smooth muscle cells to epidermal growth factor. Relaxed single smooth muscle cells were obtained by gentle trituration of the digested tissue with a plastic pipette. Blood vessel dilation is due to blockage of calcium channels in smooth muscle cells or inhibition of sodium-calcium ion exchange. It also predisposes to thrombosis, leucocyte adhesion, and mural smooth muscle proliferation. Anticholinergics block muscarinic receptors on airway smooth muscle and possibly on submucosal gland cells. Show More Sentences A prominent smooth muscle component, reminiscent of uterine wall myometrium, accounted for most of the cyst wall. The myometrium is a thick coat containing smooth muscle and abundant connective tissues. The inhaled bronchodilators relieve only the airway narrowing from spasm of the bronchial smooth muscle. Topical phenylephrine, which increases the tone of the sphincter smooth muscle, is under development. On the other hand, melatonin reportedly induced contraction of bovine bronchial smooth muscle. Blood vessels only work when both endothelia and vascular smooth muscle are bound together. The profile parallels that observed for bradykinin stimulated smooth muscle cells. It is possible to isolate a multipotent stem cell from neural crest that can give rise to neurons, glia, and smooth muscle. The difficulty of predicting the biological behavior of uterine smooth muscle tumors has been recognized for many years. The smooth muscle portion of the esophagus is innervated by neurons within the dorsal motor nucleus of the vagus. Large continuous masses of eosinophils were situated within the extracellular matrix, beneath the bronchiolar smooth muscle layer. There is mucous metaplasia, enlargement of the mass of bronchiolar smooth muscle, and loss of alveolar attachments. The airways are surrounded by a type of involuntary muscle known as smooth muscle. This smooth muscle is the involuntary sphincter of the posterior urethra in the male. Normal epididymis and smooth muscle bundles were present at the edge of the tumor. The hemorrhoidectomy specimens showed a stroma of connective tissue containing many blood vessels, and interwoven bundles of smooth muscle. The stromal component, however, typically appears benign and predominantly consists of interlacing bundles of smooth muscle. There was bowel wall fibrosis and strialike hyperplasia of smooth muscle in the stenotic zones. Here, striated muscle is replaced by smooth muscle, the two types of muscle interdigitating over several centimeters. These authors found ultrastructural evidence of altered endothelial and smooth muscle cells within chorionic vessels exhibiting HEV-like lesions. Show More Sentences The antioxidative properties of statins also prevent the development of cardiac and smooth muscle cell hypertrophy. It is known to form a highly hydrated pericellular coat around chondrocytes, fibrosarcoma, and smooth muscle cells. He also suggested an expiratory wave of peristaltic smooth muscle contraction starting from the periphery to aid in exhalation. In addition, localised radiotherapy at the time of stent implantation helps to reduce proliferation of smooth muscle. Medial or intimal smooth muscle cells had weak or absent expression of these molecules. The force of contraction declines slightly as it advances, reaching a nadir at about the level where the muscle becomes smooth muscle. Associated with the follicle are sebaceous glands and the arrector pili smooth muscle fiber bundle. Serotonin is a biogenic amine that modulates smooth muscle contractions of the crop and gizzard of the earthworm, Lumbricus terrestris. This includes those of the parasympathetic nervous system in the heart, glandular tissue, and smooth muscle. High potency as an antagonist of 5-HT in isolated smooth muscle preparations was not correlated with high potency as a psychotomimetic. They consist of thin sheets of collagen and smooth muscle with an endothelial covering. Single stomach smooth muscle cells were isolated by enzymatic dissociation with trypsin and collagenase as described previously. Weak immunoreactivity for NOS2 in the normoxia plus saline group was present in bronchiolar and vascular smooth muscle, bronchiolar epithelium, and Clara cells. Your ligaments, tendons, bones and skeletal muscles are all held together by collagen, as well as the smooth muscle tissue like your blood vessels, digestive tract and organs. The esophageal musculature is striated in the proximal esophagus and is separated by a short transition zone from the smooth muscle portion of the esophagus. Deeper in the airway wall there is cartilage and smooth muscle. This tonic contraction is mostly myogenic, due to special properties of this smooth muscle, but it is modified by excitatory and inhibitory nerves. However, at this point in time robust registration of fast and small changes in the corpus cavernosum smooth muscle action potential is not possible. Mast cells produce basic fibroblast growth factor, which is a potent mitogenic factor for proliferation of smooth muscle cells, myofibroblasts, and fibroblasts. Contraction may be sustained, as in the smooth muscle cells present in the blood vessels or airways, or rhythmic, as in the cells of the myometrium and gastrointestinal tract. Show More Sentences The accumulating cells are either macrophages or smooth muscle cells. Desmin and vinculin are functionally related proteins that are present in the membrane-associated dense bodies in the sarcolemma of the smooth muscle cells. Thus, our measurements appear to be particularly well suited for characterization of dynamic actin rheology during airway smooth muscle contraction. A second major difference between smooth and striated muscle is that smooth muscle contains a unique myosin light-chain subunit known as p-light chain. Products of complement activation cause smooth muscle contraction and increased vascular permeability and induce degranulation of phagocytic cells, mast cells, and basophils. Vasodilators, such as acetylcholine and bradykinin, do not exert their effects upon the vascular smooth muscle cell in the absence of the overlying endothelium. Tumor cells also infiltrated the smooth muscle of the ciliary body. Isoprenaline exerts its effects by relaxing the smooth muscle tissues lining the finely branched tubular network of bronchioles that surround the lungs. We measured the tracheal smooth muscle reactivity to methacholine. Sildenafil, the first oral drug marketed for the treatment of erectile dysfunction, relaxes smooth muscle in the corpora cavernosa, enabling erection during arousal. Recently, evidence that glyceryl trinitrate's relaxant effect on uterine smooth muscle may be enhanced during pregnancy has raised interest in its use. However, as with bronchial smooth muscle hypertrophy, it can be expected that the remodeled vessels may exhibit altered reactivity to contractile or relaxant agents. They may be composed purely of mature adipocytes, or of brown fat, or of adipocytes in combination with mature smooth muscle and vascular elements. I wouldn't be surprised if the thin eating champs were born with weak pyloric sphincters, or exhibit higher capacity for smooth muscle relaxation. Postganglionic parasympathetic nerves mediate both cholinergic contractions and nonadrenergic, noncholinergic relaxations of smooth muscle in the airway. A relaxation of cervical smooth muscle facilitates dilation. The B-type is of smooth muscle fiber type that is mostly found in the metapodium, and functions to maintain greater tension. The lesion shows diffuse positivity for CD68 and vimentin, and negativity for smooth muscle actin, desmin, and epithelial markers. Theophylline, also known as dimethylxanthine, was used as positive control because of its use as smooth muscle relaxant. Histologically, tumoral proliferation is observed with smooth muscle, fat tissue, and vascular channels surrounded by a fibrous. Show More Sentences Such mechanism of myorelaxant activity of imperatorin was also suggested in regard to vascular smooth muscle. For example, smooth muscle cells have been shown to the origin of osteochondroblastic cells. Conventional medical therapy for an enlarged prostate includes alpha-blocker drugs such as Flomax to relax the smooth muscle in the prostate. Liposarcoma and leiomyosarcoma are specific types of STS that occur in fat cells or smooth muscle cells. Histopathologically, AML is composed of mature adipose cell, smooth muscle cell, and thick-walled vessels. When exposed to nicotine, smooth muscle cells already riled up by inflammation formed ringlike structures that started the invasion. Pig bronchial rings were used in vitro to determine if loratadine pre-treatment could counteract histamine-induced constriction of smooth muscle. Sildenafil works by affecting the cyclic guanosine monophosphate and vascular smooth muscle. The dephosphorylation step is mediated by myosin phosphatase, the primary effector of smooth muscle relaxation. To make the vessels, the scientists cultured smooth muscle cells, obtained from human blood vessels, on a biodegradable micromesh tube. Immunohistochemically, most cells stained positive for p63, and smooth muscle actin highlighted the myoepithelial cells within the lesion. It is part of the nervine group of herbals and has proven anti-spasmodic effects to smooth muscle. Second, the spindle cell's ultrastructures have features consistent with myofibroblastic and smooth muscle cell differentiations. Both disorders involve the autonomic nervous system and an alteration in contractility and smooth muscle tone. Vascular endothelial growth factor secretion has also been observed in human tissue-engineered vessels using smooth muscle cells. Cyclic nucleotide phosphodiesterase isoenzymes in the human detrusor smooth muscle. In their experience, verapamil is more potent vascular smooth muscle relaxant. Tropomysin 4 expression is enhanced in dedifferentiating smooth muscle cells in vitro and during atherogenesis. The smooth muscle relaxation effect is produced through the activation of guanyalate cyclase and resulting increase in intracellular cyclic guanosine 3-5-monophosphate. Achalasia is a condition in which there is loss of peristalsis of the smooth muscle of the esophagus, and failure of relaxation of the lower esophageal sphincter. Show More Sentences Utilize form and texture by mixing in coarse and fine leaves with interesting bark, such as the smooth muscle tone of ironwood or the shaggy exterior of river birch. Most of the literature characterizing vulvar smooth muscle tumors comprises single case reports with reviews of the literature, and few large case series exist. The inner part, the so-called lissosphincter, surrounds the urethra and is formed by circular and longitudinally oriented smooth muscle cell layers. Other species of Leontice like Leontice leontopetalum and its alkaloid petaline chloride has been tested on guinea pig isolated smooth muscle and heart. Their unique lungs have airways that are highly reinforced with cartilaginous rings and smooth muscle, and alveoli that completely deflate during deeper dives. Bundles of smooth muscle and interlobular fibroplasia were seen. Coiling around prey is accomplished largely by the return of the tentilla to their inactive state, but the coils may be tightened by smooth muscle. Because the myometrium of the uterus is comprised of smooth muscle, it stands to reason that CCBs could be effective in suppressing early uterine contractions. This system is primarily responsible for innervating the smooth muscle layers of the alimentary canal and can function totally independent of the central nervous system. Unlike the skeletal and cardiac muscles, smooth muscle cells either can rest in their final form, which allows vessels to contract, or can divide into new cells. Unlike skeletal and cardiac muscles, smooth muscle cells can either rest in their final form, which allows vessels to contract, or they can divide into new cells. Glomus tumors have been divided into 3 groups, depending on the varying proportions of glomus cells, vascular structures, and smooth muscle tissue present. The structure of the small intestine consists of a layer of cells, a mucosal lining, a connective tissue support, and a fine submucosal smooth muscle layer. Examples from Classical Literature Besides these places where smooth muscle is found there are some in the eye. The tunica media is composed of intermingled bundles of elastic tissue, smooth muscle fibers, and some fibrous tissue. His thighs, rounded under a close-fitting gray uniform, were bulging with smooth muscle. These bands of smooth muscle fibers are also encountered, though less well developed, in the mesentery of birds and mammals. This tube is reinforced in different ways by connective tissue, smooth muscle fibers, and fibroelastic tissue. The other two kinds of muscle, heart muscle and smooth muscle, must have a word of description. There are, however, two points of superiority about smooth muscle, which fit in well with its special task. Since the stomach walls are of smooth muscle they adjust themselves to the progress of the meal. Find more words! 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What is the plural of smooth muscle? Use our Sentence Generator Nearby Words smoothly smoothing smoothies smoothie smoothest smoothes smoothness smooth out smooth-running smooths smooth sailing smooth-shaven