| No doubt, slavery had a profound impact on the Americas, but more than simply a supply of forced labor. |
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| Other projects could have a much more profound impact on the intellectual property landscape. |
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| The obedience experiments had a profound impact within academic social psychology, altering the central message of the discipline itself. |
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| Seeing only the degradation of their culture reflected in the mass media has a profound impact on Native youth. |
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| A desperate dearth of top-shelf artworks is having a profound impact on Australia's salerooms. |
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| It is the relatively unremarked legislation that can often have the most profound impact on the day-to-day lives of ordinary people. |
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| All of these essays are by authors whose sociological vision has had a profound impact on our culture. |
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| However he was ejected from the seminary at the age of 25, a move which was to have a profound impact on his life. |
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| But at a certain point, there is a level of desensitization, and that desensitization has a very profound impact for cultural development. |
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| The legendary contralto had a profound impact on the cultural life of this country. |
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| Two other special education teachers in the junior high school had a lasting and profound impact on my day-to-day survival as a first-year special education teacher. |
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| The economic reform and open door policy in post-Mao China, has not only produced fundamental changes in its domestic economy but also created a profound impact on the world economy as well. |
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| Over the long term, they will make a far more profound impact. |
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| This encounter had a profound impact on her career. As his protégé and with his encouragement she made congenital heart disease her life study. |
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| The soft-spoken mother of five could not read or write and her illiteracy had a profound impact on her children's health. |
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| The determined observance of these restraints by a number of dedicated Yogis can and will have a profound impact upon society. |
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| We know military sonar has a significant and profound impact upon marine mammals. |
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| Hyperhidrosis has a profound impact on social interactions and work related activities. |
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| A recent study in the US has highlighted the profound impact that chemic als c an have if exposure occur s during puberty. |
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| The projects have a profound impact on the division of work and on management decisions. |
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| Removal actions have a profound impact on an indivdual's liberty and suits for legal malpractice are not a practical or satisfying remedy. |
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| Eczema flares are not only physically painful, but they also have a profound impact on patients' quality of life and emotional well-being. |
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| These measures had a profound impact on some sectors which modernized their production methods to meet the war's limitless demand for arms and munitions. |
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| This has had a profound impact on our legal system in at least two very important respects. |
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| However, it is clear that language shifts have a profound impact on the community's sense of identity. |
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| New technology is already having a profound impact on the financial services industry. |
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| When it comes to international bridges and tunnels, we have shown that it has a profound impact on trade. |
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| Thus, the euro has and will continue to have in the years to come a profound impact upon both the euro area and the world economy. |
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| The current global economic and financial crisis has had a profound impact on private investment in infrastructure. |
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| The distribution of a community in a particular territory can have a profound impact. |
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| The education of women and girls has a profound impact on the well being of the family and society as a whole. |
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| An especially cold winter or hot summer can have a profound impact on energy use. |
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| That is having a profound impact on the work of courts in all areas of the law. |
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| And that clearly has a profound impact on us, given how heavily we rely on our largest trading partner to grow our own economy. |
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| Their victimization can have the same profound impact on children and extended family members. |
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| We all know that this is an area that has a direct and profound impact on all working people. |
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| Indeed, the decisions that will be made here in the coming weeks will have a profound impact on that becoming a reality. |
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| This had a profound impact on the results of the survey and the variability measures. |
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| From Shark Fin Soup to habitat destruction, we show what humans are doing to drive sharks into extinction. And we show the profound impact that their extinction would have on every last one of us. |
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| Blavatsky had a profound impact on pioneer geometric artists like Hilma af Klint and Wassily Kandinsky. |
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| On-Board Diagnostic regulations have had a profound impact on the North American ECU aftermarket. |
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| Technology also had a profound impact on research and clinical care. |
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| Reducing incivil behaviors among employees has a profound impact on culture and, most importantly, performance. |
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| It has had a profound impact on aboriginal businesses across the country, many of whom have had to go out of business because of the cancellation of this project. |
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| He follows others for whom the sea has had a profound impact and whose poetry and writing have influenced our vision of ourselves as a Maritime nation, despite the hugeness of our land mass. |
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| She had a profound impact on our company and on each one of us personally. |
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| The pervasiveness of slavery, the lateness of its abolition, and the fact that nothing was done to turn former slaves into citizens all combined to have a profound impact on Brazilian society. |
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| This issue of World Conservation explores the many ways our health challenges are linked to the environment and the profound impact we are having on the planet. |
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| Solutions exist that have profound impact. |
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| Here, sites with the most profound impact. |
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| The member for Windsor West has been a tireless advocate to ensure that the people of Windsor are involved in decisions that have a profound impact in that area. |
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| These issues, when combined with the technology issues and opportunities, could have a profound impact on the direction of Canada's national strategy. |
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| Late King Abdullah bin Abdulaziz, the sixth king of Saudi Arabia, had a profound impact on the Saudi economy and oil policy. |
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| To date, microarrays for gene expression have made a profound impact in the pharmaceutical and biomedical worlds. |
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| Speaking from experience, I believe the opportunities I have had not only to learn the language, but to be immersed in a Francophone environment, have had a profound impact on me, both personally and professionally. |
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| I agree that the Medical Discharge of any employee should be a last consideration due to the profound impact such a disposition can have on not only the employee but the employer. |
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| This may seem like a minor issue but it could have a profound impact on the uptake of digital technology and, particularly, the way it is used by public service broadcasters. |
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| An even scarier thought is that if peers have replaced us as the ones who matter most, what is missing in those peer relationships is going to have the most profound impact. |
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| The growth in entrepreneurship in this province has a profound impact on our economic landscape, and this is expected to continue for some time to come. |
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| While eczema can have a profound impact on individuals and families, people who have the information and support they need tend to feel less isolated and misunderstood. |
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| The stability and integrity of government are not only important for a country's leadership, but are also significant factors that have profound impact on society itself. |
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| Wadham was then under the guidance of John Wilkins, who had a profound impact on Hooke and those around him. |
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| Marx's ideas have had a profound impact on world politics and intellectual thought. |
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| From the sixth to the eighteenth centuries, the maritime history of Europe had a profound impact on the rest of the world. |
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| His ethics of nature and wildlife preservation had a profound impact on the environmental movement, with his ecocentric or holistic ethics regarding land. |
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| The Highland Clearances and widespread emigration significantly weakened Gaelic language and culture and had a profound impact on the nature of Gaelic poetry. |
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| Microalbumin quickly became a textbook example of a new laboratory test with profound impact on treatment and long-term outcomes of patients with a chronic disease. |
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| The spread of humans and their large and increasing population has had a profound impact on large areas of the environment and millions of native species worldwide. |
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