| Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. |
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| The approach is based on eavesdropping on a single DNA polymerase molecule working in a continuous, processive manner. |
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| Poxviruses replicate in the host cytoplasm using a processive polymerase composed of several viral proteins. |
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| As a result, extension rates better reflect the kinetics seen in PCR with processive extension of a defined template for more reproducible activity measurements. |
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