| It does not appear to be a classic heterophile antibody, nor is it a paraprotein. |
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| If the specimen does not contain IM heterophile antibodies, a colored line will not appear in this region indicating a negative result. |
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| If the specimen contains IM heterophile antibodies, a colored line will appear in the test line region indicating a positive result. |
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| Based upon the results of the three reference ELISA tests and the heterophile test, the specimens were categorized into one of 4 groups as indicated in Table 1 below. |
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| Performance characteristics of this device have not been established with specimens containing heterophile antibodies which are known to cause false positive results in various immunoassays. |
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| Diagnosis of IM is made based on the presence of heterophile antibodies. |
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| Though heterophile antibody tests are often ordered to confirm diagnosis of IM, this test has a high false-negative rate early in the course of the disease. |
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| Despite the strong accuracy and reliability of currently used hormone assays, some limitations should be reviewed, such as interference by autoantibodies, heterophile antibodies or macroprolactin and the hook effect. |
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| A third goal was to develop a cost-effective testing algorithm for the management of patients with heterophile antibody-negative infectious mononucleosis. |
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| This suggests that the interference is not an anti-mouse heterophile, and that the Scantibodies HBT may be nonspecifically blocking human immunoglobulin. |
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