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What does vacuolated mean?

Looking for the meaning or definition of the word vacuolated? Here's what it means.

Adjective
  1. Having vacuoles
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Examples
Cytoplasm is abundant, pale to eosinophilic, and can be granular or vacuolated.
Also evident were occasional large papillary fragments lined by large cells with abundant clear to vacuolated cytoplasm.
Macrophages were highly vacuolated and frequently contained phagocytized debris or leukocytophagia.
In addition, extremely vacuolated oocytes with nuclear shrinkage and elongated mitochondria with a few cristae were observed as well.
The hippocampus had vacuolated myelinated fibers with breaks in continuity.
The microspores at releasing time are vacuolated and they have peripheral nucleus.

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