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What is a tophus?

What is a tophus? Here are some definitions.

Noun
  1. (medicine) A deposit of monosodium urate crystals in the body, caused by high levels of uric acid in the blood.
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Once a tophus has developed, this is visible on MRI imaging, but unfortunately the findings are not pathognomonic.
The slides stained with HE and our method were examined with a light microscope for the presence of urate crystals and diagnostic histologic features of gouty tophus.
Four years later, he obtained uric acid from a gouty tophus.
Diagnosis is by removing fluid from an affected joint or tophus and identifying urate crystals under a polarized-light microscope.
One swallow does not make a summer, but one tophus makes gout and one crescent malaria.
The exclusion criteria were patients who presented with gout but without tophus and patients with other crystal illnesses.

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