We used PPF to test the hypothesis that TDE, galanthamine and ACh reduce synaptic responses by presynaptically depressing glutamatergic release. |
Cocaine blocks the reuptake of catecholamines presynaptically. |
We find that the occurrence of glia postsynaptically is strikingly higher than presynaptically, in both types of synapses. |
Pregabalin works presynaptically on overactive calcium channels and can reduce the symptoms of neuropathic pain. |
The neurotoxins act presynaptically, initially releasing acetylcholine, followed by an interference with or blockade of its release. |
Glutamate is released presynaptically and binds to a postsynaptic receptor gating a cation-selective channel, thus depolarizing the post-synaptic cell. |