The peptide bond is very stable, its spontaneous hydrolysis is almost nil, but it can be hydrolysed by chemical or enzymatic. |
An acetyl group was attached to residue 22 to mimic the preceding peptide bond and the C-terminal carboxylate was protonated. |
Trypsin cleaves the peptide bond on the C-ter side of the amino acids lysine and arginine. |
Peptide bond formation is a condensation reaction leading to the polymerization of amino acids into peptides and proteins. |
Thermolysin cuts the peptide bond on the N-terminal side of hydrophobic amino acids. |
As a result, studies of uncoded peptide bond formation are founded in using NCAs as substrates for mimicking prebiotic processes. |