We also analyze the evidence for the presence of a disease mutation after inferring the ancestry of a locus. |
The 25-bp insertion causes a frameshift mutation and creates stop codons in all three reading frames. |
We estimate that reversion of the lac mutation is about one-tenth as likely as a null frameshift mutation in a typical gene. |
Many country sounds are so terrifying they could easily have come from the throat of a rabid bat mutation or a savage, cross-bred boar-wolf. |
However, such covariant mutation can also occur within closely related groups. |
Whereas a translation error is like an inkblot marring one copy of a book, a mutation is a flaw in the printing plate, reproduced in every copy. |