| They looked at 1 709 patients with a history of stroke or transient ischaemic attack randomised to fixed doses of perindopril and indapamide. |
| Patients were randomized to treatment with indapamide with or without perindopril, or to placebo. |
| The results indicated that DURO-TAK® adhesive 87-2852 is a suitable and compatible polymer for the development of transdermal drug delivery systems for indapamide. |
| It showed that the routine administration of a fixed combination of perindopril and indapamide improves survival and reduces the risk of heart and kidney disease. |
| Indeed, indapamide bound to CA II has no interactions with active site water molecules. |
| All patients received the ACE inhibitor perindoprill and the diuretic indapamide or placebo for blood pressure control. |
