The approval of Exjade is expected to greatly enhance the acceptance of iron chelation therapy, especially for children. |
Effective iron chelation therapy is required to reduce body iron levels in regularly transfused patients. |
They can act directly by entering the redox reactions, and indirectly by chelation of iron. |
Product manufacturers have attempted to mimic this process by combining minerals with amino acids in the process of chelation. |
Desferal, a Novartis treatment, has been the gold standard of iron chelation for decades. |
Hydrolysis promotes chelation, or the formation of network-type atomic connections, until the mass gels. |