Linezolid was stopped when the patient was admitted to hospital with anemia, pure red cell aplasia and severe peripheral neuropathy. |
At the time of aplasia, the child with sickle cell disease is highly contagious. |
Antibody-mediated pure red cell aplasia has been reported in a very rare number of patients exposed to AranespĀ® subcutaneously. |
Because this disease is virtually always fatal due to the profound bone marrow aplasia, management is not well defined and is rarely successful. |
Measurements of thyroid hormone and cortisol levels should be considered because hypogonadism may occur with pituitary aplasia. |
Germinal cell aplasia or sterility in offspring of mothers receiving busulfan during pregnancy has not been reported in humans. |