| Therefore, we stratified the single group analyses, including only the propositus of each family. |
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| Key relatives included siblings, parents, offspring, grandparents, first uncles and aunts, and the propositus. |
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| This variant was named Hb Gorwihl after the city where the propositus lived. |
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| The propositus was an elderly man who passed on the disorder to three of his four children and 9 of 14 grandchildren. |
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| A gift under which the beneficiaries are defined by reference to a purely personal relationship to a named propositus cannot on principle be a valid charitable gift. |
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| Mutations were checked against parental DNA for each propositus. |
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| A low cobalamin concentration had been noted several years earlier in the 57-year-old propositus, for which she received intermittent cobalamin injections. |
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