| The very premise of the novel relies on this sense of a missing cause, giving the story a lacunal effect. |
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| I had hoped to demonstrate it by injection of the lacunal system, but the attempts were unsuccessful. |
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| If this balance is disrupted the size and distribution of the lacunal membranes are severely altered. |
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| Thus the nephrocyte lacunal membranes are in constant flux — with vigorous endocytosis sustained by equally dynamic membrane replenishment. |
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| Whether these different endocytic pathways are spatially segregated to tip versus lacunal membranes has not been investigated. |
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| Unfortunately, most indicators have been developed separately, thus producing a lacunal picture of countries' overall institutional environment. |
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