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What is an antagonist?

What is an antagonist? Here are some definitions.

Noun
  1. An opponent or enemy.
  2. One who antagonizes or stirs.
  3. (biochemistry) A chemical that binds to a receptor but does not produce a physiological response, blocking the action of agonist chemicals.
  4. The main character or force opposing the protagonist in a literary work or drama.
  5. (anatomy) A muscle that acts in opposition to another.
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It is working on a version containing naltrexone, an opiate antagonist that would block oxycodone's euphoric effects once the pill was crushed.
Nalmefene, another opioid antagonist, is similar to naltrexone but without FDA approval for treatment of alcohol dependence.
Since the claw flexor muscle in insects has no antagonist, claws and arolium are moved back by elastic recoil of stretched exocuticle.
The screen comes alive when either the protagonist, or his worthy antagonist, are present.
The bear, wolf, coyote, fisher, wolverine, otter, and lynx prey upon the beaver who is, nevertheless, a powerful antagonist when at bay.
Small studies have suggested that the opiate antagonist naltrexone is effective as an adjuvant therapy for treating alcohol addiction.

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