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What is an acme?

What is an acme? Here are some definitions.

Noun
  1. The top or highest point; pinnacle; culmination. [c. 1610]
  2. (medicine) The crisis or height of a disease.
  3. Mature age; full bloom of life.
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Examples
Whether he has plummeted, reached the acme or is in a spiritual limbo is for him to decide.
Her eyes slowly rose from its foot to its acme, taking in its enormity and impassability.
But Sanjay seems today like an adumbration, rather than the acme, of authoritarian possibilities in India.
He gets a job working for IBM, the acme of corporate, conformist paternalism, the antithesis of bohemianism.
She is the acme of generosity, wanting to know if I've a sweetheart so she can give her some jewellery, and which Broadway show I'd like to see.
Britain, he declared, and British laws and achievements, were the acme of human civilization.

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